CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 51 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04549506
NCT04549506N/ACompleted

The Hypothesis of Emotional Empathy Imbalance in Autism: Conscious and Non-conscious Processing of Emotional Faces

Yawei Cheng·observational·Posted Sep 16, 2020·Updated Sep 16, 2020

In Brief

An observational study for Autism Spectrum Disorder. Completed, enrolled 51 participants.

Detailed Summary

Empathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD) should have a deficit of cognitive empathy and a surfeit of emotional empathy. Considering that inconsistent amygdala reactivity to emotional faces might be ascribed to aberrant attention in ASD, the investigators hypothesized to investigate if there would be an imbalance between conscious and nonconscious emotional processing. This fMRI study recruited 26 youths and young adults with autism spectrum disorder and 25 matched controls, and measured their amygdala reactivity and functional connectivity in response to conscious and nonconscious (backward masked) perception of threatening faces. Keywords: Autism Spectrum Disorder; amygdala reactivity; emotional processing; fMRI

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedSep 16, 2020
Enrollment StartApr 19, 2014
Primary CompletionSep 21, 2016
Study CompletionJun 16, 2017
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 5.8 years ago