CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 361 enrolled
Drug / intervention
Cognitive Processing Therapy +3 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04552301
NCT04552301N/ACompleted

Assessing Inflammatory and Behavioral Pathways Linking PTSD to Increased Asthma Morbidity in WTC Workers

Icahn School of Medicine at Mount Sinai·interventional·Posted Sep 17, 2020·Updated Sep 19, 2024

In Brief

A clinical study evaluating Cognitive Processing Therapy, Psychotherapy, and 2 other interventions for Asthma and PTSD. Completed, enrolled 361 participants across 1 site.

Detailed Summary

Asthma and post-traumatic stress disorder (PTSD) are the most common conditions in World Trade Center (WTC) rescue and recovery workers. In this study, the study team will evaluate the interplay of biological and behavioral mechanisms explaining the relationship of PTSD with increase asthma morbidity and adapt and pilot test a novel intervention to improve outcomes of WTC workers.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma, PTSD
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedSep 17, 2020
Enrollment StartAug 18, 2020
Primary CompletionJun 1, 2022
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 5.8 years ago

Interventions

Cognitive Processing Therapybehavioral

Integrated CPT. CPT is based on a social cognitive theory of PTSD that focuses on how the traumatic event is construed and coped with by a person who is trying to regain a sense of mastery and control in his or her life. The asthma components that will be integrated into the intervention include psychoeducation about asthma, barriers to asthma self-care, asthma medication education, inhaler technique, and asthma self-management behaviors.

Psychotherapybehavioral

The Study Interventionist will conduct generalized supportive psychotherapy with the participants to provide emotional support for both PTSD and general education for asthma.

Targeted Asthma Educationbehavioral

The manualized 10-session program of asthma self-management

General Asthma Educationbehavioral

A 10-session program of similar time