CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 200 enrolled
Drug / intervention
ENB +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04553809
NCT04553809N/ACompleted

The Efficacy of Combining Endoscopic Modalities for the Diagnosis of Solitary Pulmonary Lesions

Amanda Dandanell Juul·interventional·Posted Sep 17, 2020·Updated May 14, 2025

In Brief

A clinical study evaluating ENB and ENB in combination with rEBUS for Lung Cancer. Completed, enrolled 200 participants across 1 site.

Detailed Summary

Lung cancer is the primary cause of cancer related deaths in Denmark. In order to improve the prognosis diagnosis in earlier stages are needed. This will however require improved sampling techniques from very small lung lesions. One method involves the use of a radial ultrasound probe inserted in the working channel of the bronchoscope, to more accurately identify the lung lesions before sampling them (rEBUS). The other method involves the use of electromagnetic navigation bronchoscopy (ENB) to guide the operator to the lung lesion. This study aims to determine whether a combination of rEBUS and ENB is superior to ENB alone in biopsy sampling. The study will be conducted as a non-blinded RCT. Furthermore, we will make an estimate of the hospital costs of the entire diagnostic work up for lung cancer when combining ENB and rEBUS compared to ENB alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLung Cancer
CountriesDenmark
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedSep 17, 2020
Enrollment StartOct 12, 2020
Primary CompletionAug 30, 2024
Study CompletionMar 1, 2025
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 5.8 years ago

Interventions

ENBprocedure

ENB for biopsy sampling of peripheral lung lesion

ENB in combination with rEBUSprocedure

The combination of ENB and rEBUS for biopsy sampling of peripheral lung lesions