CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 499 enrolled
Drug / intervention
Pridopidine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04556656
NCT04556656Phase 3Completed

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Arm, Multicenter Study Evaluating the Efficacy and Safety of Pridopidine in Patients With Early Stage of Huntington Disease

Prilenia·interventional·Posted Sep 21, 2020·Updated Mar 12, 2025

In Brief

A Phase 3 clinical trial evaluating Pridopidine and Placebo for Huntington Disease. Completed, enrolled 499 participants across 58 sites in 11 countries.

Detailed Summary

This study will evaluate the efficacy and safety of pridopidine 45mg twice daily (BID) in patients with early stage manifest Huntington Disease (HD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustria, Canada, Czechia, France, Germany, Italy, Netherlands, Poland, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedSep 21, 2020
Enrollment StartOct 16, 2020
Primary CompletionMar 14, 2023
Study CompletionMar 21, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 5.8 years ago

Interventions

Pridopidinedrug

Pridopidine hard gelatin capsule

Placebodrug

Pridopidine-matching placebo hard gelatin capsule