CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 36 enrolled
Drug / intervention
Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponade +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04557527
NCT04557527N/ACompleted
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Suprachoroidal Visco-buckling for the Treatment of Rhegmatogenous Retinal Detachment: A Randomized, Controlled, Feasibility Trial

King's College Hospital NHS Trust·interventional·Posted Sep 21, 2020·Updated Aug 6, 2025

In Brief

A clinical study evaluating Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponade and Suprachoroidal viscobuckle with 2.3% Sodium hyaluronate (Healon 5 Ophthalmic viscoelastic device) for Retinal Detachment With Break. Completed, enrolled 36 participants across 6 sites.

Detailed Summary

The study compares standard surgery for retinal detachment (RD) (vitrectomy, cryotherapy and gas) with a surgical variation that replaces the intraocular gas tamponade with suprachoroidal injection of viscoelastic underneath the break that caused the retinal detachment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRetinal Detachment With Break
CountriesUnited Kingdom
CollaboratorsNorfolk and Norwich University Hospitals NHS Foundation Trust, St Thomas' Hospital, London, University of Sunderland, Moorfields Eye Hospital NHS Foundation Trust, Mid and South Essex NHS Foundation Trust, Sheffield Teaching Hospitals NHS Foundation Trust

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedSep 21, 2020
Enrollment StartFeb 7, 2022
Primary CompletionDec 31, 2024
Study CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 5.8 years ago

Interventions

Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponadeprocedure

Conventional pars plana vitrectomy procedure is used to treat rhegmatogenous retinal detachment- laser or cryo retinopexy intraocular gas tamponade (SF6, C2F6 or C3F8) are chosen according to the number and size of the causative retinal break(s) and surgeons clinical judgement

Suprachoroidal viscobuckle with 2.3% Sodium hyaluronate (Healon 5 Ophthalmic viscoelastic device)device

After drainage of subretinal fluid, approximately 0.5 ml of Healon 5 is injected in to the suprachoroidal space underlying the retinal break. Laser retinopexy is applied around the break .