CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 43 enrolled
Drug / intervention
Research CBCTdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04565457
NCT04565457N/ACompleted
CompareCT.gov

A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality

University of Colorado, Denver·interventional·Posted Sep 25, 2020·Updated May 6, 2026

In Brief

A clinical study evaluating Research CBCT for Prostate Cancer and 2 related conditions. Completed, enrolled 43 participants across 2 sites.

Detailed Summary

This is Pilot study that investigates the CBCT(Cone beam computed tomography) image quality improvement provided by the 2D antiscatter grid technology. The primary objective is to assess the improvement in tissue visualization in an observer study, which will be conducted in a blinded fashion.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsProstate Cancer, Head and Neck Cancers, Upper Abdomen Cancers
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedSep 25, 2020
Enrollment StartApr 21, 2023
Primary CompletionMay 28, 2025
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 5.8 years ago

Interventions

Research CBCTdevice

Each study participant will receive one additional CBCT scan, with 2D antiscatter grid in place. This is the only intervention in the study, referred as research CBCT scan, and it will be performed on one of the days during the participant's radiation treatment course. This additional research CBCT scan will be used strictly for the objectives of this study. It will not be used as part of the standard clinical care, such as imaging guidance of participant's radiation treatment or diagnostic purposes. To deliver participant's radiation treatment under CBCT guidance, a standard clinical CBCT scan will be acquired, as in standard clinical care protocols.