CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 375 target
Drug / intervention
Communicationother
Likely dose
Not stated in record
Key inclusion· 4
  • ✓Enrolled in NEPTUNE observational study (biopsied or non-biopsied cohorts)
  • ✓Potentially eligible for specific NEPTUNE Match partnering trial
  • ✓Receives regular nephrology care at NEPTUNE study site
  • ✓Able to provide informed consent/assent
Key exclusion· 2
  • ✕Not enrolled in NEPTUNE observational study
  • ✕Non-English or non-Spanish speaking

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04571658
NCT04571658N/ARecruitingHigh Momentum
Long Recruiting
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Implementing Precision Medicine for Glomerular Diseases in the Nephrotic Syndrome Study Network (NEPTUNE)

University of Michigan·interventional·Posted Oct 1, 2020·Updated Jun 10, 2026

In Brief

A clinical study evaluating Communication for Nephrotic Syndrome in Children and 8 related conditions. Currently recruiting, targeting 375 participants across 16 sites.

Signals

Enrolling ahead of pace

Detailed Summary

NEPTUNE Match is an additional opportunity offered to NEPTUNE study participants to prospectively recruit and communicate patient-specific clinical trial matching with kidney patients and their physician investigators.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNephrotic Syndrome in Children, Focal Segmental Glomerulosclerosis, Minimal Change Disease, Minimal Change Nephrotic Syndrome, Membranous Nephropathy, FSGS, MCD, MCD - Minimal Change Disease, Alport Syndrome
CountriesUnited States
CollaboratorsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Timeline

N/ARecruiting
2021202220232024202520262027202820292030
First PostedOct 1, 2020
Enrollment StartMay 2, 2022
Primary CompletionDec 30, 2029
TodayJul 2, 2026
Enrollment to primary: 7.7 yearsPosted 5.8 years agoPrimary completion in 3.5 years

Arms & Interventions

NEPTUNE Match Participantsother

Approximately 375 participants will be consented from the NEPTUNE observational study with age and demographic groups representing the patient population in the NEPTUNE study site geographical areas. NEPTUNE observational cohort eligibility includes: participants in NEPTUNE observational cohort A are of any age and have a biopsy-confirmed diagnosis of Focal Segmental Glomerulosclerosis (FSGS), Minimal Change Disease (MCD), or Membranous Nephropathy (MN). Participants in NEPTUNE observational cohort B have documented NS based on proteinuria, serum albumin, and/or edema with age of onset less than 19 years.

Other: Communication

Interventions

Communicationother

The NEPTUNE Match study includes an interdisciplinary Communication Team that will translate findings from the Molecular Nephrology Board (MNB) to inform patients of the matching assessment with ongoing clinical trials. This team has considerable experience with conveying complex biomedical research information to patients and families and includes experts in precision nephrology, nephrology patient \[adult and pediatric\] communication, and health education.