CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 24 enrolled
Drug / intervention
HistoSonics Systemdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04573881
NCT04573881N/AActive

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK)

HistoSonics, Inc.·interventional·Posted Oct 5, 2020·Updated Jan 12, 2026

In Brief

A clinical study evaluating HistoSonics System for Liver Neoplasms and 2 related conditions. Active but no longer recruiting, targeting 24 participants across 6 sites in 4 countries.

Detailed Summary

This trial is a single arm, non-randomized prospective trial. The objective of this trial is to evaluate the efficacy and safety of the HistoSonics System for the treatment of primary or metastatic tumors located in the liver.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Italy, Spain, United Kingdom
Collaborators--

Timeline

N/AActive
2021202220232024202520262027
First PostedOct 5, 2020
Enrollment StartJun 4, 2021
Primary CompletionSep 29, 2022
Study CompletionAug 1, 2027
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 5.7 years ago

Interventions

HistoSonics Systemdevice

The HistoSonics System - intended for the destruction of liver tissue using histotripsy, a non-thermal, mechanical process using focused ultrasound.