CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 52 enrolled
Drug / intervention
Prolonged Proned Positioning +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04581811
NCT04581811N/ACompleted
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Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS): A Pilot Study

University of Alabama at Birmingham·interventional·Posted Oct 9, 2020·Updated Mar 31, 2022

In Brief

A clinical study evaluating Prolonged Proned Positioning and Traditional Proning Arm for ARDS and 2 related conditions. Completed, enrolled 52 participants across 1 site.

Detailed Summary

Prone positioning is one of the few therapies known to improve mortality in ARDS. Traditionally, patients are proned for 16 hours per 24 hour period. Some retrospective data suggests improvement may persist beyond 16 hours. We aim to perform a pilot study comparing traditional prone positioning to prolonged prone positioning in patients with COVID-induced ARDS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsARDS, Covid19, Acute Hypoxemic Respiratory Failure
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedOct 9, 2020
Enrollment StartNov 10, 2020
Primary CompletionMar 20, 2021
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 5.7 years ago

Interventions

Prolonged Proned Positioningother

Patients will be placed in the prone position for 24 hours followed by 8 hours supine for consecutive periods for the duration of the study period

Traditional Proning Armother

Patients will be placed in the prone position for 16 hours followed by 8 hours supine for consecutive periods for the duration of the study period