At a glance
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Metabolism Informed Smoking Treatment in Medicaid and Medicare Patients: The MIST RCT
In Brief
A Phase 3 clinical trial evaluating Post-discharge automated phone calls (IVR) with option to connect with a tobacco coach., Nicotine Replacement Therapy, and 2 other interventions for Smoking. Completed, enrolled 606 participants across 1 site.
Detailed Summary
This phase 3 randomized controlled trial will test Metabolism-Informed Smoking Treatment (MIST), a precision approach to smoking treatment that biologically tailors medication selection to nicotine metabolism.
Study Details
Timeline
Interventions
Automated calls to assess smoking status, medication use, and additional support for quit attempt.
FDA-approved forms of nicotine replacement therapy for smoking cessation.
FDA-approved smoking cessation medication.
Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy. NMR is a blood test to measure how fast the body breaks down nicotine.