CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 15 enrolled
Drug / intervention
BI 730357 +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04590937
NCT04590937Phase 1Completed

The Effect of BI 730357 on the Pharmacokinetics of Rosuvastatin, Digoxin, Metformin and Furosemide Given as a Cocktail - an Open-label, Non-randomised, 2-period Fixed-sequence Trial in Healthy Subjects

Boehringer Ingelheim·interventional·Posted Oct 19, 2020·Updated Sep 6, 2023

In Brief

A Phase 1 clinical trial evaluating BI 730357, CRESTOR®, and 3 other interventions for Healthy. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The main objective of this trial is to investigate the effect of BI 730357 under steady state conditions on the pharmacokinetics of digoxin, furosemide, metformin and rosuvastatin given as a cocktail (Reference, R: cocktail alone; Test T: cocktail given under steady state conditions of BI 730357).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedOct 19, 2020
Enrollment StartOct 20, 2020
Primary CompletionJan 11, 2021
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 5.7 years ago

Interventions

BI 730357drug

Film-coated tablet

CRESTOR®drug

Film-coated tablet

Lenoxin®drug

Tablet

MetfoLiquid GeriaSan®drug

Oral solution

Lasix®drug

Oral solution