CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 5 enrolled
Drug / intervention
TAVT-18 (sirolimus)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04595513
NCT04595513Phase 2Completed

Stopping TSC Onset and Progression 2: Epilepsy Prevention in TSC Infants

Children's Hospital Medical Center, Cincinnati·interventional·Posted Oct 20, 2020·Updated May 16, 2024

In Brief

A Phase 2 clinical trial evaluating TAVT-18 (sirolimus) for Tuberous Sclerosis Complex and Epilepsy. Completed, enrolled 5 participants across 1 site.

Detailed Summary

This phase I/II clinical trial is an open-label clinical trial design to verify safety and dosing for TAVT-18 (sirolimus) powder for oral solution in TSC infants (N=5).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedOct 20, 2020
Enrollment StartSep 8, 2020
Primary CompletionDec 15, 2022
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 5.7 years ago

Interventions

TAVT-18 (sirolimus)drug

The investigational drug product to be used in this study is TAVT-18, a proprietary formulation of sirolimus in clinical development, by Tavanta Therapeutics, Inc. It is provided in a powder formulation in pre-measured vials.