CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 119 enrolled
Drug / intervention
Chemotherapy +1 moredrug
Likely dose
Chemotherapy 1000mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04603586
NCT04603586N/ACompleted

A Prospective Phase Ⅱ Clinical Study of Stereotactic Radiotherapy Combined With Chemotherapy With Different Biological Effective Doses (<70gy vs. >70Gy) in Locally Advanced Pancreatic Cancer

Changhai Hospital·interventional·Posted Oct 27, 2020·Updated Oct 20, 2025

In Brief

A clinical study evaluating SBRT and Chemotherapy for Treatment. Completed, enrolled 119 participants across 2 sites.

Detailed Summary

The aim of this study is to compare the safety and efficacy of SBRT in LAPC with different biological effective dose (BED) (\<70Gy Vs.\>70Gy ) , to identify a dose range that could achieve better survival benefit and minimize the toxicity of radiotherapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTreatment
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedOct 27, 2020
Enrollment StartNov 10, 2020
Primary CompletionAug 15, 2025
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 5.7 years ago

Interventions

SBRTradiation

SBRT: in 5-6 fractions with CyberKnife

Chemotherapydrug

Gemcitabine 1000mg/m\^2 and nab-paclitaxel 125mg/m\^2, administered intravenously, on day 1 and 8 of a 21-day cycle for six cycles