CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
Attention Process Training (APT-II)behavioral
Likely dose
Not stated in record
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Search/NCT04606953
NCT04606953N/ACompleted

Working Memory Training With Attention Process Training (APT-II) in Older Adults With Mild Cognitive Impairment : Impacts on Cognition and Ecological Activities

University of Paris 5 - Rene Descartes·interventional·Posted Oct 28, 2020·Updated Sep 29, 2021

In Brief

A clinical study evaluating Attention Process Training (APT-II) for Mild Cognitive Impairment and Alzheimer Disease. Completed, enrolled 24 participants across 1 site.

Detailed Summary

Older adults with Mild Cognitive Impairment (MCI) have an increased risk of developing dementia but do not meet the criteria for dementia. Cognitive rehabilitation makes it possible to compensate, at least in part, for cognitive deficits with the ultimate goal of reducing their impact in everyday life. The objective of the research is to evaluate the short- and long-term effectiveness and generalization of an attention and working memory training program (APT-II) on cognition and ecological activities in MCI patients with a randomized controlled trial. Thirty MCI patients will be randomly assigned between a "cognitive training with APT-II" condition and a control (routine care) condition. The intervention will consist of an 8-week individual cognitive training program (2 sessions/week), training different attentional components and working memory. This has the advantage of insisting on the transfer of the acquired knowledge in sessions to daily activities. To evaluate the effectiveness of the treatment, cognitive and functional follow-up measures (including a virtual reality task) are administered at several time intervals. This project should contribute to better management of cognitive disorders by offering a new standardized rehabilitation tool in French to clinical practice.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedOct 28, 2020
Enrollment StartFeb 1, 2019
Primary CompletionJul 30, 2021
Study CompletionSep 27, 2021
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 5.7 years ago

Interventions

Attention Process Training (APT-II)behavioral

The exercises target different attentional components and working memory in the auditory-visual modalities. They are of increasing difficulty while being adapted to the profile of each patient in order to maximize the effects on cognitive reserve. During the sessions, the emphasis is on generalizing the gains to the most problematic daily activities in order to reduce the impact of cognitive disorders in patients' daily life.