CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 234 enrolled
Drug / intervention
Etrasimod +1 moredrug
Likely dose
Etrasimod 2 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04607837
NCT04607837Phase 2Completed

A Randomized, Double Blind, Placebo Controlled, 52 Week Study to Assess the Efficacy and Safety of Etrasimod in Subjects With Moderately Active Ulcerative Colitis

Pfizer·interventional·Posted Oct 29, 2020·Updated Jul 15, 2025

In Brief

A Phase 2 clinical trial evaluating Etrasimod and Placebo for Ulcerative Colitis. Completed, enrolled 234 participants across 288 sites in 18 countries.

Detailed Summary

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for moderately active ulcerative colitis in adult participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Belarus, Belgium, Bulgaria, Czechia, France, Georgia, Germany, Hungary, Israel, Italy, Poland, Portugal, Russia, South Korea, Spain, Ukraine, United States

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedOct 29, 2020
Enrollment StartApr 12, 2021
Primary CompletionJun 19, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 5.7 years ago

Interventions

Etrasimoddrug

Etrasimod 2 mg tablet by mouth, once daily up to 52 weeks of treatment

Placebodrug

Etrasimod matching placebo tablet by mouth, once daily up to 52 weeks of treatment