At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 22 enrolled
Drug / intervention
Rapamycin Topical Ointment +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
An Innovative Proof-of-concept Approach to Identify Age-modulating Drugs Capable of Reversing Inflammation and Re-setting the Epigenetic Clock (Topical-RAPA)
The University of Texas Health Science Center at San Antonio·interventional·Posted Oct 29, 2020·Updated Jul 19, 2023
In Brief
A Early Phase 1 clinical trial evaluating Rapamycin Topical Ointment and Placebo for Aging and 2 related conditions. Completed, enrolled 22 participants across 1 site.
Detailed Summary
Topical Rapamycin ointment will be applied to participant forearms to test whether epigenetic changes in the skin are elicited.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAging, Epigenetics, Inflammatory Mediators
CountriesUnited States
CollaboratorsNational Institute on Aging (NIA)
Timeline
Early Ph 1CompletedFinished
202120222023202420252026
First PostedOct 2020
Enrollment StartApr 2021
Primary CompletionApr 2022
TodayJul 2026
First PostedOct 29, 2020
Enrollment StartApr 28, 2021
Primary CompletionApr 15, 2022
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 5.7 years ago
Interventions
Rapamycin Topical Ointmentdrug
8% topical rapamycin ointment
Placeboother
Petrolatum ointment containing no active ingredient