CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 8 enrolled
Drug / intervention
tDCS and CO-OP Groupcombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04617548
NCT04617548Phase 1Completed

Feasibility Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke

University of Missouri-Columbia·interventional·Posted Nov 5, 2020·Updated Feb 11, 2022

In Brief

A Phase 1 clinical trial evaluating tDCS and CO-OP Group for Chronic Stroke. Completed, enrolled 8 participants across 1 site.

Detailed Summary

This project seeks to evaluate the acceptability feasibility, practicality feasibility, and preliminary effect of combining transcranial direct current stimulation (tDCS) and metacognitive strategy training (MCST) in individuals with chronic stroke.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Stroke
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2020202120222023202420252026
First PostedNov 5, 2020
Enrollment StartJan 1, 2020
Primary CompletionDec 31, 2021
Study CompletionJan 1, 2022
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 5.7 years ago

Interventions

tDCS and CO-OP Groupcombination

Transcranial direct current stimulation modulates the excitability of targeted brain regions, and is thought to facilitate or inhibit neuroplasticity. Participants will receive anodal tDCS (1.5 mA) to the dorsolateral prefrontal cortex (dlPFC) for 20 minutes at the beginning of each session. CO-OP focuses on learning of a global problem-solving strategy, Goal-Plan-Do-Check (GPDC), within the performance of participant-chosen goals. Use of a broadly applicable strategy and meaningful activity ensures the intervention is salient to the participant and increases likelihood of transfer. Uniquely, therapists applying CO-OP use guided discovery methods to support participants in analyzing their own performance of a given task and generating potential solutions for improving performance. Participants become equipped with these skills through repetitive application of the Goal-Plan-Do-Check process.The intervention focuses on learning GPDC with gradual withdrawal of guided discovery methods.