CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 41 enrolled
Drug / intervention
Rimegepant +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04629950
NCT04629950Phase 2Completed

A Pilot Study of Rimegepant in Moderate Plaque-type Psoriasis

Weill Medical College of Cornell University·interventional·Posted Nov 16, 2020·Updated Jul 17, 2025

In Brief

A Phase 2 clinical trial evaluating Rimegepant and Placebo for Psoriasis. Completed, enrolled 41 participants across 2 sites.

Detailed Summary

The purpose of this study is to examine the use of a new investigational medication for the treatment of moderate plaque-type psoriasis. The study medication is rimegepant, an orally administered small molecule competitive inhibitor of the calcitonin gene-related peptide (CGRP) receptor. This medication, rimegepant, has been approved by the FDA under the trade name Nurtec for the treatment of acute migraine. However, rimegepant has not been studied in the treatment of moderate plaque-type psoriasis and is investigational for this indication.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPsoriasis
CountriesUnited States
CollaboratorsPfizer

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedNov 16, 2020
Enrollment StartJan 19, 2021
Primary CompletionAug 20, 2024
Study CompletionNov 18, 2024
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 5.6 years ago

Interventions

Rimegepantdrug

Active Agent

Placebodrug

Placebo Comparator