CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 37 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04630301
NCT04630301N/ACompleted

Pleural Manometry for the Characterization of Spontaneous and Tension Pneumothorax

Johns Hopkins University·observational·Posted Nov 16, 2020·Updated Oct 20, 2025

In Brief

An observational study for Pneumothorax and Tension Pneumothorax. Completed, enrolled 37 participants across 4 sites.

Detailed Summary

Intrapleural pressures have been shown to be a useful clinical predictor in pleural effusions, however it's utility has not been described in pneumothorax. Data on intrapleural pressures in pneumothorax are limited. Furthermore, the pleural pressure in tension pneumothorax is theorized to be greater than atmospheric pressure, though this has never been verified. Pneumothorax is primarily treated with a tube thoracostomy. This observational study will record intrapleural pressures in participants with pneumothorax undergoing a tube thoracostomy. Clinical outcomes of participants will then be monitored for need for pleurodesis, intrabronchial valve placement, and video assisted thoracoscopic surgery (VATS) to identify a correlation with intrapleural pressure.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsMedline Industries

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedNov 16, 2020
Enrollment StartFeb 17, 2021
Primary CompletionJun 30, 2025
Study CompletionJul 31, 2025
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 5.6 years ago