At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Impact of High Versus Standard Enteral Protein Provision on Functional Recovery Following Intensive Care Admission: a Randomized Controlled, Multicenter, Parallel Group Trial in Mechanically Ventilated, Critically Ill Patients
In Brief
A clinical study evaluating PRECISe protocol EN 8g protein/100kcal and PRECISe protocol EN 5g protein/100kcal for Critical Illness and Intensive Care Unit Acquired Weakness. Completed, enrolled 935 participants across 10 sites in 2 countries.
Detailed Summary
Rapid skeletal muscle wasting during critical illness had a detrimental impact on both short and long term outcomes following ICU admission. Increased dietary protein delivery might attenuate skeletal muscle wasting and its subsequent effects on post-ICU function. The investigators will conduct a 935 patient, randomised controlled, quadruple blinded parallel group trial to determine whether enteral nutrition with increased protein content in mechanically ventilated, critically ill patients is able to improve functional recovery.
Study Details
Timeline
Interventions
Enteral feed containing 8g protein/100kcal
Enteral feed containing 5g protein/100kcal