CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 46 enrolled
Drug / intervention
Standard Dose of Unfractionated Heparin +1 moredrug
Likely dose
Standard Dose of Unfractionated Heparin 5,000 unitsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04635839
NCT04635839Phase 4Completed
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Randomized Control Trial of Unfractionated Heparin Thromboprophylaxis Dosing for Antepartum Hospitalizations

University of California, Los Angeles·interventional·Posted Nov 19, 2020·Updated Apr 28, 2023

In Brief

A Phase 4 clinical trial evaluating Standard Dose of Unfractionated Heparin and Gestational Age-Based Dose of Unfractionated Heparin for Pregnancy Related and Antepartum DVT. Completed, enrolled 46 participants across 1 site.

Detailed Summary

This study is a randomized control trial to compare gestational age-based dosing with standard dosing of unfractionated heparin for thromboprophylaxis of hospitalized antepartum patients. The investigators aim to determine the effect of dosing on receipt of neuraxial anesthesia and pregnancy outcomes and evaluate the pharmacokinetics and pharmacodynamics of unfractionated heparin in pregnancy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPregnancy Related, Antepartum DVT
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedNov 19, 2020
Enrollment StartDec 15, 2020
Primary CompletionMar 31, 2022
Study CompletionMay 1, 2022
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 5.6 years ago

Interventions

Standard Dose of Unfractionated Heparindrug

5,000 units subcutaneous unfractionated heparin every 12 hours

Gestational Age-Based Dose of Unfractionated Heparindrug

* First trimester (\< 14 weeks of gestation): 5,000 units subcutaneous unfractionated heparin every 12 hours * Second trimester (14-28 weeks of gestation): 7,500 units subcutaneous unfractionated heparin every 12 hours * Third trimester (\> 28 weeks of gestation): 10,000 units subcutaneous unfractionated heparin every 12 hours