CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Physical Characteristics +8 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04636255
NCT04636255N/ACompleted
CompareCT.gov

Physical Capacity Evaluation and Effects of ExerciseTraining on Hodgkin Lymphoma Survivors

University of Sao Paulo General Hospital·interventional·Posted Nov 19, 2020·Updated May 4, 2026

In Brief

A clinical study evaluating Physical Characteristics, Assessment of Heart rate variability, and 7 other interventions for Hodgkin Lymphoma, Adult and 3 related conditions. Completed, enrolled 40 participants across 1 site.

Detailed Summary

The study aims to investigate if physical capacity obtained in the cardiopulmonary exercise test can predict cardiovascular alterations in Hodgkin Lymphoma (HL) Survivors. In addition, to study the effects of exercise training on physical capacity and cardiovascular responses in these patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHodgkin Lymphoma, Adult, Cardiovascular Diseases, Radiation Effect, Chemotherapy Effect
CountriesBrazil
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedNov 19, 2020
Enrollment StartOct 21, 2017
Primary CompletionOct 21, 2022
Study CompletionOct 21, 2023
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 5.6 years ago

Interventions

Physical Characteristicsprocedure

Body Weight, Height

Assessment of Heart rate variabilityother

Holter 24h

Blood Pressure and Cardiac Autonomic Controlother

Non-invasive photoplethysmography (Finometer® PRO) monitored by the electrocardiogram and respiratory frequency by a piezoelectric chest strap.

Evaluation of Baroreflex Controlother

The magnitude and latency of the baroreflex control of the heart rate will be assessed by bivariate analysis using the autoregressive method.

Cardiac Function and Structureother

Echocardiogram

Assessment of Coronary Anatomy and Calcium Scoreother

Angiotomography

Blood Assessmentsother

Serum and Plasma will be extracted by centrifugation. NT-pro BNP (Roche™) and c-TnI (imunoassay Elecys 2010).

Physical Capacityother

Cardiopulmonary Exercise Test.

Physical Trainingprocedure

Aerobic exercise: 48 sessions of 60 minutes: 5 minutes of warm-up, 40 minutes of exercise. Resistance exercise: 10 minutes of exercise and 5 minutes of recovery.