CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 30 enrolled
Drug / intervention
Durvalumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04642469
NCT04642469Phase 3Completed

A Phase III, Randomized, Multicenter, Double-blind, Placebo-controlled Study of Durvalumab for the Treatment of Stage II-III NSCLC Patients With Minimal Residual Disease Following Surgery and Curative Intent Therapy.

AstraZeneca·interventional·Posted Nov 24, 2020·Updated Jun 25, 2024

In Brief

A Phase 3 clinical trial evaluating Durvalumab and Placebo for Carcinoma, Non- Small Cell Lung. Completed, enrolled 30 participants across 115 sites in 25 countries.

Detailed Summary

This is a Phase III double-blind, placebo-controlled study of Durvalumab versus Placebo in patients with stage II-III NSCLC who are MRD-positive following curative intent therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Belgium, Brazil, Canada, Czechia, France, Greece, Hong Kong, Hungary, India, Israel, Italy, Japan, Netherlands, Peru, Poland, Russia, Singapore, South Korea, Spain, Taiwan, Turkey (Türkiye), United States, Vietnam
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedNov 24, 2020
Enrollment StartNov 30, 2020
Primary CompletionMay 31, 2023
Study CompletionJan 15, 2024
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 5.6 years ago

Interventions

Durvalumabdrug

Intravenous administration of Durvalumab

Placeboother

Placebo Comparator