CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 100 enrolled
Drug / intervention
Bupivacain +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04646967
NCT04646967Phase 2Completed
CompareCT.gov

A Randomized Control Trial Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision

Alberta Children's Hospital·interventional·Posted Nov 30, 2020·Updated Aug 2, 2024

In Brief

A Phase 2 clinical trial evaluating Bupivacain, Sevoflurane, and 3 other interventions for Pain, Postoperative and 3 related conditions. Completed, enrolled 100 participants across 1 site.

Detailed Summary

Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse effects. This study aims to see if giving ketorolac during the operation will result in better pain control. We hypothesize that ketorolac will result in pain control similar to morphine with a lower incidence of side effects such as nausea and vomiting.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative, Phimosis, Paraphimosis, Balanitis
CountriesCanada
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedNov 30, 2020
Enrollment StartNov 25, 2022
Primary CompletionJan 25, 2024
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 5.6 years ago

Interventions

Bupivacaindrug

See active comparator description

Sevofluranedrug

See active comparator description

Acetaminophendrug

See active comparator description

Ibuprofendrug

See active comparator description

Ketorolacdrug

See experimental arm description