CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 7 enrolled
Drug / intervention
Trigeminal Nerve Stimulationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04648085
NCT04648085N/ACompleted
CompareCT.gov

Effect of Trigeminal Nerve Stimulation on Subbasal Corneal Nerve Plexus Density and Chronic Ocular Pain in Patients With Dry Eye

Instituto de Oftalmología Fundación Conde de Valenciana·interventional·Posted Dec 1, 2020·Updated Jan 18, 2022

In Brief

A clinical study evaluating Trigeminal Nerve Stimulation for Dry Eye and 2 related conditions. Completed, enrolled 7 participants across 1 site.

Detailed Summary

Individuals with dry eye tend to present with ocular pain which persists despite the use of topical treatment. This could be secondary to somatosensory impairment attributable to neuropathic pain. The purpose of this study is to evaluate the effect of trigeminal nerve stimulation (TNS) on corneal nerves and chronic ocular pain in patients with dry eye.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDry Eye, Neuropathic Pain, Eye Pain
CountriesMexico
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 1, 2020
Enrollment StartFeb 3, 2021
Primary CompletionDec 10, 2021
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 5.6 years ago

Interventions

Trigeminal Nerve Stimulationdevice

Applied to to the forehead using a self-adhesive electrode positioned bilaterally over the upper branches of the trigeminal nerve.The device generates electrical impulses allowing to stimulate the trigeminal nerve.