CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 579 enrolled
Drug / intervention
Tirzepatide +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04657016
NCT04657016Phase 3Completed

Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo After an Intensive Lifestyle Program in Participants Without Type 2 Diabetes Who Have Obesity or Are Overweight With Weight-Related Comorbidities: A Randomized, Double Blind, Placebo-Controlled Trial (SURMOUNT-3)

Eli Lilly and Company·interventional·Posted Dec 7, 2020·Updated May 16, 2024

In Brief

A Phase 3 clinical trial evaluating Tirzepatide and Placebo for Obesity and Overweight. Completed, enrolled 579 participants across 65 sites in 4 countries.

Detailed Summary

This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program. The study will last about 2 years (29 visits).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity, Overweight
CountriesArgentina, Brazil, Puerto Rico, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedDec 7, 2020
Enrollment StartMar 29, 2021
Primary CompletionApr 20, 2023
Study CompletionMay 12, 2023
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 5.6 years ago

Interventions

Tirzepatidedrug

Administered SC

Placeboother

Administered SC