CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 126 enrolled
Drug / intervention
RSVPreF3 OA investigational vaccine (GSK3844766A)biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04657198
NCT04657198Phase 2Completed

A Phase 2b, Open-label, Multi-center, Extension Study to Evaluate the Safety and Immunogenicity of a Revaccination Dose of the RSVPreF3 Older Adults (OA) Investigational Vaccine Administered Intramuscularly 18 Months Post-Dose 2 in Adults 60 Years and Older Who Participated in the RSV OA=ADJ-002 Study

GlaxoSmithKline·interventional·Posted Dec 8, 2020·Updated Jun 29, 2022

In Brief

A Phase 2 clinical trial evaluating RSVPreF3 OA investigational vaccine (GSK3844766A) for Respiratory Syncytial Virus Infections. Completed, enrolled 126 participants across 10 sites in 2 countries.

Detailed Summary

Nine different formulations of the RSVPreF3 OA investigational vaccine were tested in the parent study (NCT03814590). Based on safety and immunogenicity data from the parent study, RSVPreF3 OA investigational vaccine will be evaluated in further clinical research. Participants in selected groups will be invited to participate in this extension study. All participants who will be enrolled in the current extension study will receive the RSV investigational vaccine approximately 18 months after they received their respective dose-2 in the parent study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, United States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedDec 8, 2020
Enrollment StartDec 9, 2020
Primary CompletionJun 3, 2021
Study CompletionOct 25, 2021
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 5.6 years ago

Interventions

RSVPreF3 OA investigational vaccine (GSK3844766A)biological

RSVPreF3 OA investigational vaccine administered intramuscularly in the deltoid region of the non-dominant arm, at Day 1 (18 months post-Dose 2 in the RSV OA=ADJ-002 parent study).