CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 41 enrolled
Drug / intervention
Hydrogen Peroxide +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04659928
NCT04659928Phase 4Completed

Evaluation of Aerosol in a Dental Clinic

The University of Texas Health Science Center, Houston·interventional·Posted Dec 9, 2020·Updated Jul 8, 2025

In Brief

A Phase 4 clinical trial evaluating High volume evacuation (HVE), Extraoral vacuum aspirator (EVA), and 2 other interventions for Covid19. Completed, enrolled 41 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the effectiveness of external evacuation units and mouth rinses during aerosol generating procedures in a dental clinic and to determine the risk level to the dental practitioners during aerosol generating procedures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCovid19
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedDec 9, 2020
Enrollment StartJul 21, 2021
Primary CompletionMay 2, 2024
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 5.6 years ago

Interventions

High volume evacuation (HVE)device

Intra oral suction will be done and during the procedure,bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab. Patient will be given a mouth rinse.

Extraoral vacuum aspirator (EVA)device

Extraoral suction connected to dental suction will be used and bacterial colony forming units (cfus) will be captured during dental care by placing large format petri dishes containing bacterial culture media in the dental operatory with open lids. Once aerosol capture is complete, petri dishes will be incubated and quantified under BSL-2 safety conditions in the lab. Patient will be given mouth rinse.

Hydrogen Peroxidedrug

Subjects will be given 1.5 % Oral Solution of hydrogen peroxide mouth rinse

Placebodrug

Subjects will be given a placebo (plain water) mouth rinse