CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Social Support +3 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04661878
NCT04661878N/ACompleted
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Piloting a Smartphone App to Improve Treatment Adherence Among South African Adolescents Living With HIV

Duke University·interventional·Posted Dec 10, 2020·Updated Jun 13, 2025

In Brief

A clinical study evaluating Social Support, Informational Resources, and 2 other interventions for HIV Infections and Adolescent Behavior. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The overall goal of this pilot randomized-controlled trial (RCT) is to pilot MASI (MAsakhane Siphucule Impilo Yethu; Xhosa for "Let's empower each other and improve our health"), an ART adherence-supporting smartphone app with 50 adolescents and young adults living with HIV to assess its feasibility and acceptability and to explore preliminary effects on ART adherence and social support.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infections, Adolescent Behavior
CountriesSouth Africa
CollaboratorsUniversity of Cape Town, University of North Carolina, National Institute of Mental Health (NIMH), Florida State University

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 10, 2020
Enrollment StartJun 21, 2022
Primary CompletionMar 15, 2024
Study CompletionApr 2, 2024
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 5.6 years ago

Interventions

Social Supportbehavioral

The app will provide opportunities for participants to interact with each other as well as trained peer mentors to receive and provide social support.

Informational Resourcesbehavioral

The app will provide opportunities for participants to review HIV-related health information in engaging formats (e.g., activities, multi-media resources, and answer to users' health questions)

Self-Monitoring and habit formationbehavioral

The app will provide opportunities for participants to track their treatment adherence and schedule tailored reminders.

Goal setting and action planningbehavioral

The app will provide opportunities for participants to identify goals, select action items, and receive tailored feedback on the action plan.