CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 19 enrolled
Drug / intervention
Adverse Drug Reaction (ADRe) Profileother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT04663360
NCT04663360N/ACompleted
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Medication Monitoring in General Practice: Clinical Impact of Implementing a Nurse-led Adverse Drug Reaction (ADRe) Profile in Older Adults With 5 or More Prescribed Medicines

Swansea University·interventional·Posted Dec 11, 2020·Updated Oct 7, 2021

In Brief

A clinical study evaluating Adverse Drug Reaction (ADRe) Profile for Polypharmacy. Completed, enrolled 19 participants across 1 site.

Detailed Summary

Polypharmacy has the potential to harm older adults by causing cognitive impairment, falls, and hospitalisations. Many adverse drug reactions could be prevented with closer monitoring. This project will establish the effectiveness of the nurse-led intervention - the ADRe Profile - for medicines commonly prescribed in primary care and evaluate intervention implementation in general practices.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPolypharmacy
CountriesUnited Kingdom
CollaboratorsAbertawe Bro Morgannwg University Health Board, Hywel Dda Health Board

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedDec 11, 2020
Enrollment StartJan 5, 2020
Primary CompletionMay 31, 2020
Study CompletionOct 4, 2020
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 5.6 years ago

Interventions

Adverse Drug Reaction (ADRe) Profileother

ADRe asks nurses to systematically check patients for the manifestation of itemised adverse side effects or undesirable effects of their primary care medicines, as listed in the BNF and manufacturers' Summaries of Product Characteristics (SmPCs), and seminal texts documenting known ADRs. Nurses are asked to share the identified problems with prescribers and pharmacists overseeing medicines charts.