CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 500 enrolled
Drug / intervention
Structured counseling +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04663828
NCT04663828N/ACompleted

UNification of Treatments and Interventions for TInnitus Patients - Randomized Clinical Trial (UNITI-RCT)

UNITI Consortium·interventional·Posted Dec 11, 2020·Updated Aug 14, 2023

In Brief

A clinical study evaluating Structured counseling, Hearing aids, and 2 other interventions for Tinnitus. Completed, enrolled 500 participants across 1 site.

Detailed Summary

The study includes a 12-week treatment trial for chronic tinnitus patients using 4 different types of interventions (hearing aids, sound therapy, structured counseling, cognitive behavioral therapy) either as a single treatment or a combination of two treatments. There are several aims of the study: compare 1) single vs. combined treatments, 2) single treatments vs. other treatments, 3) ear and brain based interventions, 4) analyzing data of the clinical trial in combination with other recorded data (genetic and proteomic data, audiology data) to develop in silico models of tinnitus and a decision support system with the aim to aid in treatment decisions. This randomized controlled trial is harmonized over five clinical centers in Europe with the aim to include 100 patients per center and is part of the UNITI-project (UNification of treatments and Interventions for TInnitus patients) funded by the European Union's Horizon 2020 programme (grant agreement number 848261).

Study Details

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 11, 2020
Enrollment StartApr 16, 2021
Primary CompletionDec 19, 2022
Study CompletionJun 15, 2023
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 5.6 years ago

Interventions

Structured counselingother

Structured patient education and counselling is considered as providing information to patients in order to empower them to better manage their disorder

Hearing aidsdevice

Hearing aids are considered medical devices and are recommended to patients with a certain degree of hearing loss. Hearing aids amplify environmental sounds.

Cognitive behavioral therapyother

This is a structured intervention and consists of a several week program both with noise exposure and structured interviews and expert-patient as well as patient-patient interaction in groups

Sound therapyother

Several sounds and music are used for tinnitus disorder