At a glance
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A Randomised, Double-blind, Placebo-controlled, Dose-response Study of the Efficacy and Safety of MEDI7352 in Subjects With Painful Osteoarthritis of the Knee
In Brief
A Phase 2 clinical trial evaluating MEDI7352 and Placebo for Painful Osteoarthritis of the Knee. Completed, enrolled 345 participants across 41 sites in 6 countries.
Detailed Summary
This is a Phase IIb randomised, double-blind, placebo-controlled, dose-response study in participants with painful osteoarthritis (OA) of the knee. The study will assess the safety and efficacy of multiple doses of MEDI7352 compared to placebo, as well as the pharmacokinetics, pharmacodynamics and immunogenicity of MEDI7352 in participants with moderate to severe chronic pain persistent for 3 months or more not adequately controlled by standard of care treatments.
Study Details
Timeline
Interventions
Participants will receive SC injection of MEDI7352 as stated in arm description.
Participants will receive SC injection of placebo as stated in arm description.