CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 224 enrolled
Drug / intervention
NCX 4251 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04675242
NCT04675242Phase 2Completed

Multi-Center, Randomized, Double-Masked, Placebo-Controlled, Phase 2b Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension, 0.1% QD for the Treatment of Acute Exacerbations of Blepharitis (Mississippi)

Nicox Ophthalmics, Inc.·interventional·Posted Dec 19, 2020·Updated Jun 18, 2023

In Brief

A Phase 2 clinical trial evaluating NCX 4251 and Placebo for Blepharitis. Completed, enrolled 224 participants across 1 site.

Detailed Summary

This is a multi-center, randomized, double-masked, placebo-controlled, Phase 2b trial evaluating the safety and efficacy of NCX 4251 (fluticasone propionate nanocrystal) Ophthalmic Suspension 0.1% QD for the treatment of acute exacerbations of blepharitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBlepharitis
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedDec 19, 2020
Enrollment StartDec 14, 2020
Primary CompletionJun 16, 2021
Study CompletionJun 30, 2021
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 5.5 years ago

Interventions

NCX 4251drug

NCX 4251 Ophthalmic Suspension, 0.1% dosed once daily

Placebodrug

Vehicle of NCX 4251 Ophthalmic Suspension dosed once daily