At a glance
ClinicalIndex Comparison Record- ✓Histologically verified lung cancer (small-cell and non-small cell)
- ✓Referred for radiotherapy with curative intent
- ✓Radiation dose 60-66 Gy in 2-Gy fractions (other dose levels and fractionation schedules accepted)
- ✓Concurrent chemotherapy is accepted
- ✕Concurrent immunotherapy
- ✕Previous radiotherapy to the thorax
- ✕Uncontrolled malignancies
- ✕Psychological, familial, sociological or geographical conditions potentially hampering compliance
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Functional Lung Avoidance SPECT-guided (ASPECT) Radiation Therapy for Lung Cancer Patients: Phase II Randomised Clinical Trial
In Brief
A clinical study evaluating Single-photon-emission CT scan for Lung Cancer and 4 related conditions. Currently recruiting, targeting 90 participants across 2 sites in 2 countries.
Detailed Summary
Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy. Functional avoidance implies a dose plan that takes functional distribution in the lung into account, and avoids highly functional lung volumes sparing them from radiation.
Study Details
Timeline
Interventions
SPECT/CT scan is an established functional modality used in the diagnosis and monitoring of lung disease. SPECT/CT scan images pulmonary circulation, where perfused areas equate with normal functional lung