CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 52 enrolled
Drug / intervention
Brolucizumabbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04679935
NCT04679935Phase 4Completed

A 52-week, Two Arm, Randomized, Open-label, Multicenter Study Assessing the Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens for Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration

Novartis Pharmaceuticals·interventional·Posted Dec 22, 2020·Updated Sep 26, 2025

In Brief

A Phase 4 clinical trial evaluating Brolucizumab for Age-related Macular Degeneration. Completed, enrolled 52 participants across 19 sites in 2 countries.

Detailed Summary

The purpose of this study was to evaluate the efficacy and safety of two different brolucizumab 6 mg dosing regimens in patients with visual impairment due to age-related macular degeneration (AMD) who have previously received anti-VEGF (vascular endothelial growth factor) treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Switzerland
Collaborators--

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedDec 22, 2020
Enrollment StartJul 13, 2021
Primary CompletionJan 31, 2024
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 5.5 years ago

Interventions

Brolucizumabbiological

Intravitreal injection