CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
Bupivacaine 0.25% +2 moredrug
Likely dose
Bupivacaine 0.25% 3 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04680923
NCT04680923N/ACompleted
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Efficacy of Combined Periportal and Preperitoneal Local Anesthetic Infiltration (CPPLAI) in Laparoscopic Sleeve Gastrectomy Patients

King Khalid University Hospital·interventional·Posted Dec 23, 2020·Updated Oct 3, 2023

In Brief

A clinical study evaluating CPPLAI, Placebo, and 1 other intervention for Obesity, Morbid and Pain, Postoperative. Completed, enrolled 120 participants across 1 site.

Detailed Summary

The high demand for bariatric surgery due to the increasing prevalence of obesity worldwide necessitate evidence-based clinical pathway such as Enhanced Recovery After Bariatric Surgery (ERABS). The paradigm of surgery has been shifted from open to laparoscopic in morbidly obese patients. Laparoscopic Sleeve Gastrectomy (LSG) is the most common procedure performed in our institute for sustained weight loss and amelioration of obesity-related comorbidities. Pain control in ERABS is one of the key factors for improved outcomes. Surgery induced acute postoperative pain, stress response and fatigue lead to prolonged convalescence and hospital stay. Optimal titrated safe postoperative pain management in LSG patients still remains a challenge.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity, Morbid, Pain, Postoperative
CountriesSaudi Arabia
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 23, 2020
Enrollment StartDec 8, 2020
Primary CompletionJun 7, 2021
Study CompletionJul 7, 2021
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 5.5 years ago

Interventions

CPPLAIprocedure

In this intervention, after general anesthesia patients will receive intraoperative combined periportal and preperitoneal bupivacaine 0.25% 2-3 mg/kg diluted in 40 ml normal saline.

Placeboother

In this intervention, after general anesthesia patients will receive intraoperative combined periportal and preperitoneal 40 ml of sterile water.

Bupivacaine 0.25%drug

In this intervention, after general anesthesia patients will receive intraoperative combined periportal and preperitoneal bupivacaine 0.25% 2-3 mg/kg diluted in 40 ml normal saline.