CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 481 enrolled
Drug / intervention
Axitinib +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04682587
NCT04682587N/ACompleted

A Panel-Based Chart Review Study to Examine the Effects of Axitinib Dose Reduction and Interruption for Adverse Event Management Among Patients Receiving First-Line Axitinib in Combination With Immune-Oncology Drugs for the Treatment of Advanced Renal Cell Carcinoma

Pfizer·observational·Posted Dec 24, 2020·Updated Jan 3, 2025

In Brief

An observational study evaluating Axitinib, Avelumab, and 1 other intervention for Renal Cell Carcinoma. Completed, enrolled 481 participants across 1 site.

Detailed Summary

To assess how dose reductions or treatment interruptions related to axitinib can be implemented to manage and resolve adverse events occurring among patients with advanced renal cell carcinoma treated with first-line axitinib in combination with avelumab or pembrolizumab

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 24, 2020
Enrollment StartFeb 24, 2021
Primary CompletionApr 5, 2021
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 5.5 years ago

Interventions

Axitinibdrug

Inlyta, axitinib

Avelumabdrug

Avelumab, Bavencio

Pembrolizumabdrug

Pembrolizumab, Keytruda