CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 370 enrolled
Drug / intervention
Diclofenac sodium active topical patch +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04683627
NCT04683627Phase 3Completed

A 12-Week, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase 3 Study to Evaluate the Efficacy and Safety of HP-5000 Topical System (Patch) in Subjects With Osteoarthritis Pain of the Knee

Noven Pharmaceuticals, Inc.·interventional·Posted Dec 24, 2020·Updated Sep 4, 2025

In Brief

A Phase 3 clinical trial evaluating Diclofenac sodium active topical patch and Placebo patch for Osteoarthritis Pain of the Knee. Completed, enrolled 370 participants across 10 sites.

Detailed Summary

A 12-week, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase 3 study to Evaluate the Efficacy and Safety of HP-5000 in Subjects with Osteoarthritis (OA) Pain of the Knee

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedDec 24, 2020
Enrollment StartDec 29, 2020
Primary CompletionJul 18, 2022
Study CompletionJul 25, 2022
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 5.5 years ago

Interventions

Diclofenac sodium active topical patchdrug

A topical patch with diclofenac sodium as active ingredient was used and evaluated for the treatment of OA pain of the knee.

Placebo patchdrug

A placebo patch without diclofenac sodium was used for the placebo arm.