CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 2 enrolled
Drug / intervention
F-18 16 Alpha-Fluoroestradiol +6 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04692103
NCT04692103Phase 2Active
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Serial [F-18] Fluoroestradiol (FES) PET Imaging to Evaluate Endocrine-targeted Therapy

University of Washington·interventional·Posted Dec 31, 2020·Updated Jan 22, 2026

In Brief

A Phase 2 clinical trial evaluating F-18 16 Alpha-Fluoroestradiol, Positron Emission Tomography, and 3 other interventions for Estrogen Receptor Positive and 2 related conditions. Active but no longer recruiting, targeting 2 participants across 1 site.

Detailed Summary

This clinical trial studies use of F-18 16 alpha-fluoroestradiol (\[F-18\] FES) positron emission tomography (PET)/computed tomography (CT) in measuring tumor hormone receptor expression in patients undergoing endocrine-targeted therapy for newly diagnosed breast cancer or breast cancer that has come back or spread to other places in the body. Comparing results of diagnostic procedures done before, during, and after hormone therapy may help measure a patient's response to treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEstrogen Receptor Positive, Primary or Recurrent Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
202120222023202420252026202720282029203020312032203320342035203620372038203920402041
First PostedDec 31, 2020
Enrollment StartJul 10, 2021
Primary CompletionOct 1, 2021
Study CompletionApr 30, 2041
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 5.5 years ago

Interventions

F-18 16 Alpha-Fluoroestradioldrug

Undergo F-18 FES PET/CT

Positron Emission Tomographyprocedure

Undergo F-18 FES PET/CT

Computed Tomographyprocedure

Undergo F-18 FES PET/CT

Fludeoxyglucose F-18drug

Undergo FDG PET/CT

Positron Emission Tomographyprocedure

Undergo FDG PET/CT

Computed Tomographyprocedure

Undergo FDG PET/CT

Laboratory Biomarker Analysisother

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