CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 32 enrolled
Drug / intervention
TILT-123biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04695327
NCT04695327Phase 1Completed

A Phase 1, Open-Label, Dose-escalation Clinical Trial of Tumor Necrosis Factor Alpha and Interleukin-2 Coding Oncolytic Adenovirus (TILT-123) in Patients With Injectable Solid Tumors

TILT Biotherapeutics Ltd.·interventional·Posted Jan 5, 2021·Updated Mar 6, 2026

In Brief

A Phase 1 clinical trial evaluating TILT-123 for Solid Tumor. Completed, enrolled 32 participants across 2 sites.

Detailed Summary

This is an open-label, phase 1, dose-escalation, multicenter trial evaluating the safety of oncolytic adenovirus TILT-123 as monotherapy in advanced solid tumor patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSolid Tumor
CountriesFinland
Collaborators--

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedJan 5, 2021
Enrollment StartJan 11, 2021
Primary CompletionSep 3, 2025
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 5.5 years ago

Interventions

TILT-123biological

TNFalpha and IL-2 coding oncolytic adenovirus TILT-123