CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 22 enrolled
Drug / intervention
(+)-SJ000557733 (SJ733)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04709692
NCT04709692Phase 2Completed

An Open Label Phase 2a Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of (+)-SJ000557733 (SJ733) With or Without Cobicistat in Adult Patients With Acute, Uncomplicated Malaria Over a 42 Day Period

R. Kiplin Guy·interventional·Posted Jan 14, 2021·Updated Dec 4, 2023

In Brief

A Phase 2 clinical trial evaluating (+)-SJ000557733 (SJ733) for Malaria, Falciparum and Malaria, Vivax. Completed, enrolled 22 participants across 1 site.

Detailed Summary

This Phase 2a trial recruits adult patients with uncomplicated P. vivax or P. falciparum blood-stage malaria mono-infection. The study drug SJ733 will be administered to examine its antimalarial efficacy, safety, and tolerability. This study also evaluates whether or not a fixed dose of the pharmacoenhancer cobicistat when given in combination with SJ733 significantly improves drug efficacy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPeru

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedJan 14, 2021
Enrollment StartApr 14, 2021
Primary CompletionApr 15, 2022
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 5.5 years ago

Interventions

(+)-SJ000557733 (SJ733)drug

Anti-Malarial