At a glance
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The Use of Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients: A Randomised Controlled Trial
In Brief
A clinical study evaluating Silver Diamine Fluoride, Papain-Based Gel, and 1 other intervention for Molar Incisor Hypomineralization and 2 related conditions. Completed, enrolled 38 participants across 1 site.
Detailed Summary
Molar incisor hypomineralization (MIH) is a developmental defect of enamel affecting the first permanent molar and frequently the incisors with a prevalence of 16-16.9% in Malaysia. They presented with many problems such as hypersensitivity, increase susceptibility of caries, need for recurrent complex dental treatment, and difficulty to achieve pain control. Silver Diamine Fluoride is a new form of topical fluoride that has been extensively used and recommended for the management of caries in children and adolescents. The influence of organic material removal from artificial dentine lesions by means of surface pre-treatment with deproteinizing agent show favoring result of its use on subsequent remineralization with and without fluoride. The purpose of this trial is to study the clinical outcome of SDF and papain based gel on hypomineralized teeth restored with HVGIC.
Study Details
Timeline
Interventions
A single application of SDF 38% (Riva Star) on dry affected molar for 1 minute and immediately restored using HVGIC
Papain based Gel (Papacare Duo) will be applied to the MIH affected molar for 60 seconds and repeated if required. The molar will be treated with SDF and restored using HVGIC
The molar will be restored with HVGIC