CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 101 enrolled
Drug / intervention
Durvalumab +3 moredrug
Likely dose
Durvalumab 1500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04712903
NCT04712903Phase 3Completed

A Phase IIIB, Single Arm Study, of Durvalumab in Combination With Platinum-Etoposide for Untreated Patients With Extensive-Stage Small Cell Lung Cancer Reflecting Real World Clinical Practice in Spain (CANTABRICO).

AstraZeneca·interventional·Posted Jan 15, 2021·Updated Jan 7, 2025

In Brief

A Phase 3 clinical trial evaluating Durvalumab, Cisplatin, and 2 other interventions for Small Cell Lung Carcinoma Extensive Disease. Completed, enrolled 101 participants across 34 sites.

Detailed Summary

This is a Phase IIIb, interventional, single arm, multicentre study to evaluate safety, effectivenees, use of resources and patient reporting outcomes in patients with ES-SCLC treated with durvalumab in combination with platinum-etoposide as first-line treatment in Spain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSpain
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJan 15, 2021
Enrollment StartDec 16, 2020
Primary CompletionJun 21, 2023
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 5.5 years ago

Interventions

Durvalumabdrug

Durvalumab 1500 mg via IV infusion over 60 minutes on Day 1 of each cycle.

Cisplatindrug

Cisplatin as an IV infusion per local standards (usually over 60 to 120 minutes on Day 1) of each cycle.

Etoposidedrug

Etoposide sequentially administered per local standards (usually over 30 to 60 minutes IV infusion) on Days 1, 2, and 3 of each cycle.

Carboplatindrug

Carboplatin as an IV infusion per local standards (usually over 30 to 60 minutes on Day 1) of each cycle.