CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 65 enrolled
Drug / intervention
The DyaMX Devicedevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04725890
NCT04725890N/ACompleted

Safety and Feasibility of Endoscopic Application of a Novel Therapy for Duodenal Mucosal Regeneration in the Treatment of Type II Diabetes

Endogenex, Inc.·interventional·Posted Jan 27, 2021·Updated Jan 22, 2026

In Brief

A clinical study evaluating The DyaMX Device for Type 2 Diabetes. Completed, enrolled 65 participants across 2 sites.

Detailed Summary

This is an open-label study to assess the safety and feasibility of the DyaMX device for endoscopic duodenal mucosal regeneration in individuals with type 2 diabetes inadequately controlled on glucose-lowering medications.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes
CountriesAustralia
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJan 27, 2021
Enrollment StartApr 20, 2021
Primary CompletionMar 1, 2024
Study CompletionDec 22, 2024
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 5.4 years ago

Interventions

The DyaMX Devicedevice

The DyaMX device is designed to induce duodenal mucosal regeneration using pulsed electric field. The DyaMX procedure is a non-surgical, endoscopic procedure.