CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Pilocarpine microneedle patch +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04732195
NCT04732195N/ACompleted
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A Pilot Study to Compare the Efficacy of Pilocarpine Microneedles With Iontophoresis Method for Sweat Induction in Healthy Human Subjects

Emory University·interventional·Posted Feb 1, 2021·Updated May 22, 2023

In Brief

A clinical study evaluating Pilocarpine microneedle patch and Pilocarpine Iontophoresis for Cystic Fibrosis. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The investigators want to test in this non-randomized clinical trial a new method of administrating Pilocarpine medicine into the skin during the Sweat testing process that does not use any electrical current.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCystic Fibrosis
CountriesUnited States
CollaboratorsGeorgia Institute of Technology

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedFeb 1, 2021
Enrollment StartJan 20, 2022
Primary CompletionMar 17, 2022
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 5.4 years ago

Interventions

Pilocarpine microneedle patchdevice

Each microneedle (MN) patch contains an array of solid, water-soluble, micron-scale needles that encapsulate the medication (Pilocarpine). The patch form can be placed directly on the skin.

Pilocarpine Iontophoresisdevice

Pilocarpine Iontophoresis is a process of transdermal pilocarpine delivery by use of a voltage gradient on the skin. An agar gel disc containing pilocarpine is placed under the electrodes which are connected to the Macroduct 3700 Sweat Inducer device.