CI

At a glance

ClinicalIndex Comparison Record
Phase 3Active· 1,720 enrolled
Drug / intervention
RSVPreF3 OA investigational vaccinebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04732871
NCT04732871Phase 3Active

A Phase 3, Randomized, Open-label, Multi-country Study to Evaluate the Immunogenicity, Safety, Reactogenicity and Persistence of a Single Dose of the RSVPreF3 OA Investigational Vaccine and Different Revaccination Schedules in Adults Aged 60 Years and Above

GlaxoSmithKline·interventional·Posted Feb 1, 2021·Updated Mar 20, 2026

In Brief

A Phase 3 clinical trial evaluating RSVPreF3 OA investigational vaccine for Respiratory Syncytial Virus Infections. Active but no longer recruiting, targeting 1,720 participants across 45 sites in 5 countries.

Detailed Summary

The purpose of this study is to assess the safety, reactogenicity, immunogenicity and long-term persistence of immune response up to 5 years following a single dose vaccination of GSK's investigational vaccine RSVPreF3 OA, in adults aged 60 years and above. The study will also evaluate the immunogenicity, safety and reactogenicity of additional vaccine doses given according to different revaccination schedules.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFinland, Germany, Japan, Taiwan, United States
Collaborators--

Timeline

Phase 3Active
2021202220232024202520262027
First PostedFeb 1, 2021
Enrollment StartFeb 15, 2021
Primary CompletionJun 6, 2022
Study CompletionFeb 19, 2027
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 5.4 years ago

Interventions

RSVPreF3 OA investigational vaccinebiological

RSVPreF3 OA investigational vaccine administered intramuscularly in the deltoid region of the non-dominant arm.