CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,226 enrolled
Drug / intervention
Tranexamic acid injection +1 moredrug
Likely dose
Tranexamic acid injection 1gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04733157
NCT04733157Phase 3Completed
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The Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Caesarean Section

University of Zimbabwe·interventional·Posted Feb 1, 2021·Updated Mar 20, 2023

In Brief

A Phase 3 clinical trial evaluating Tranexamic acid injection and Normal saline placebo for Postpartum Hemorrhage. Completed, enrolled 1,226 participants across 2 sites.

Detailed Summary

This study seeks to determine if the using tranexamic acid prophylactically at caesarean section will prevent postpartum haemorrhage which is a major cause of maternal mortality in Zimbabwe and globally.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostpartum Hemorrhage
CountriesZimbabwe
CollaboratorsFogarty International Center of the National Institute of Health

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedFeb 1, 2021
Enrollment StartMar 23, 2021
Primary CompletionDec 14, 2021
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 5.4 years ago

Interventions

Tranexamic acid injectiondrug

Tranexamic 1g administered intravenously at the onset of skin incision at caesarean section

Normal saline placeboother

10ml of normal saline will be administered intravenously at onset of skin incision at caesarean section to the placebo group