CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 139 enrolled
Drug / intervention
0.02% Betamethasone Sodium Phosphate +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04734210
NCT04734210Phase 2Completed

A Multicenter, Randomized, Double-Masked, Dose-Ranging Study To Compare The Ocular Safety, Tolerability, And Efficacy Of SURF-200 Ophthalmic Solution (0.02% And 0.04% Betamethasone Sodium Phosphate) To Vehicle In Subjects With A Diagnosis Of Dry Eye Disease And Experiencing An Episodic Flare Up

Surface Ophthalmics, Inc.·interventional·Posted Feb 2, 2021·Updated Jun 4, 2025

In Brief

A Phase 2 clinical trial evaluating 0.02% Betamethasone Sodium Phosphate, 0.04% Betamethasone Sodium Phosphate, and 1 other intervention for Dry Eye Disease. Completed, enrolled 139 participants across 28 sites.

Detailed Summary

SURF-200 is being studied in people experiencing an episodic flare-up of their dry eye disease. SURF-200 is an investigational drug (which means the study drug is currently being tested) in the form of a sterile eye drop. The purpose of this research study is to see how well SURF-200 works and what side effects there are, and to compare it with vehicle (placebo). The study will involve about 120 study participants at multiple research sites in the United States.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDry Eye Disease
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedFeb 2, 2021
Enrollment StartJan 7, 2021
Primary CompletionOct 12, 2022
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 5.4 years ago

Interventions

0.02% Betamethasone Sodium Phosphatedrug

topical corticosteroid solution

0.04% Betamethasone Sodium Phosphatedrug

topical corticosteroid solution

Placebodrug

topical vehicle solution