CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 41 enrolled
Drug / intervention
clenbuterol (CST-103), nadolol (CST-107), matching placebodrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04739423
NCT04739423Phase 2Completed

A Phase II, Randomized, Placebo-Controlled, Double-Blind, Crossover, Study of the Pharmacodynamic Effects of CST-103 Co-administered With CST-107 on the Central Nervous System in Subjects With Neurodegenerative Disorders

CuraSen Therapeutics, Inc.·interventional·Posted Feb 4, 2021·Updated Dec 2, 2024

In Brief

A Phase 2 clinical trial evaluating clenbuterol (CST-103), nadolol (CST-107), matching placebo for Mild Cognitive Impairment, Lewy Body Dementia, Parkinson's Disease Rapid Eye Movement Sleep Behavior Disorder, Parkinson's Disease Dementia. Completed, enrolled 41 participants across 7 sites in 3 countries.

Detailed Summary

This is a Phase II, randomized, placebo-controlled, double-blind, crossover study on the CNS and pharmacodynamic effects of clenbuterol (CST-103) co-administered with nadolol (CST-107) in 4 subject populations with Neurodegenerative Disorders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, New Zealand, United Kingdom
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedFeb 4, 2021
Enrollment StartJun 28, 2021
Primary CompletionJul 4, 2022
Study CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 5.4 years ago

Interventions

clenbuterol (CST-103), nadolol (CST-107), matching placebodrug

clenbuterol (CST-103) and matching placebo orange capsules; nadolol (CST-107) and matching placebo white capsules