CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 94 enrolled
Drug / intervention
Periarticular Injection (PAI) +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04749615
NCT04749615Phase 4Completed

Does Periarticular Injection (PAI) Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving Adductor Canal Block and Infiltration Between the Popliteal Artery and the Capsule of the Posterior Knee (ACB&IPACK)? A Blinded, Randomized Controlled Trial.

Hospital for Special Surgery, New York·interventional·Posted Feb 11, 2021·Updated Dec 27, 2024

In Brief

A Phase 4 clinical trial evaluating Periarticular Injection (PAI) and Saline Control Periarticular Injection (PAI) for Total Knee Athroplasty. Completed, enrolled 94 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to determine whether Periarticular Injection (PAI) alongside Adductor Canal Block (ACB) and Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block can decrease post-operative pain in patients undergoing primary total knee arthroplasty. The main question it aims to answer is: • Is ACB/IPACK without PAI as effective as ACB/IPACK with PAI for TKA patients? Participants will be assigned to one of the following groups at random: * ACB/PACK with PAI * ACB/IPACK with saline injection Participants will also be asked to complete pre- and post-operative questionnaires.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedFeb 11, 2021
Enrollment StartDec 17, 2020
Primary CompletionApr 1, 2022
Study CompletionJul 1, 2022
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 5.4 years ago

Interventions

Periarticular Injection (PAI)drug

PAI is a widely-utilized, surgeon-performed, analgesic intervention for TKA patients.

Saline Control Periarticular Injection (PAI)drug

equal volume of saline will be used in place of analgesics used in PAI injections